Live surgeryApril 29, 20232:22:338 speakersAvailable in: EN / IT

Hot Topics in Upper GI Surgery: ICG in Esophagectomy, Gastrectomy and Lymphadenectomy

Four hot topics in upper GI surgery: use of ICG in Ivor Lewis esophagectomy, subtotal vs total gastrectomy, D2 vs D2+ lymphadenectomy, and organ-sparing surgery in early gastric cancer.
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Clinical case

Adenocarcinoma gastrico distale T1b cN0

Patient framing as discussed at case introduction
SexM
Age64
StagecT1N0M0 (poi pT1b N0, 22 linfonodi negativi, G2)
DiagnosisAdenocarcinoma gastrico distale T1b cN0
Prior treatmentNessuno
Clinical historyBuone condizioni generali, lesione piccola distale identificata endoscopicamente
NotesCaso operato in diretta durante precedente sessione Permanent School: marcatura endoscopica ICG, wedge resection laparoscopica con sentinel node navigation, esame estemporaneo del pezzo, dimissione in 3a giornata. Vengono presentati anche altri 4 casi simili di chirurgia di risparmio d'organo gastrico.

Overview

Episode of the Permanent School on ICG Surgery dedicated to 'Hot Topics' in upper gastrointestinal surgery, moderated by Domenico D'Ugo with organizational direction by Gian Luca Baiocchi and the support of Stryker. The session is structured in four blocks, each with a speaker and a 'shooter' who critically comments on the presentation. In the first block, Ugo Elmore (San Raffaele, Rosati group) presents the Milan school's experience on the use of indocyanine green in minimally invasive Ivor Lewis esophagectomy: assessment of gastric conduit perfusion (Angio-Green Esophagus Study, SPY quantification), identification of the thoracic duct via inguinal lymph node injection to prevent chylothorax, and lymph node mapping (still preliminary). Uberto Fumagalli serves as shooter, highlighting biases and the maturity of the evidence. Next, Fabio Cianchi (Florence) addresses the choice between total and subtotal gastrectomy, focusing on resection margins, Lauren histotype, and Japanese vs Western guidelines; Federico Marchesi comments from a laparoscopic perspective. In the third block, Simone Giacopuzzi (Verona) discusses D2 vs D2+, historically reviewing Sasako's JCOG 9501, the role of lymph node stations 13, 14V, 12P, 8P and 16, the era of neoadjuvant therapy and molecular biology (MSI), with commentary by Stefano Rausei. Gian Luca Baiocchi (Cremona) closes by presenting Sentinel Node Navigation Surgery in light of the recent results of the Korean SENORITA trial (JCO 2022), with his own initial series of organ-sparing surgery in early gastric cancer, emphasizing the need for strict selection criteria, dedicated informed consent, and tight follow-up protocols. D'Ugo concludes by proposing the development of 'gastric oncoplasty' guidelines.

Topics

  • Use of ICG for gastric conduit perfusion in esophagectomy
  • Fluorescence identification of the thoracic duct for chylothorax prevention
  • ICG lymph node mapping in esophagectomy
  • Total vs subtotal gastrectomy: indications and resection margins
  • Lauren classification and impact on surgical margins
  • Proximal gastrectomy and reconstructive techniques
  • D2 vs D2+ lymphadenectomy in gastric cancer
  • Role of molecular biology (MSI) in surgical decision-making
  • Laparoscopic lymphadenectomy and lymph node compliance
  • Sentinel Node Navigation Surgery and the SENORITA trial
  • Organ-sparing surgery in early gastric cancer
  • Quantification of ICG fluorescence

Tools used

ICG (verde di indocianina)Sistema Stryker SPY (quantificazione fluorescenza)Reference card StrykerSuturatrice circolareRastrello laparoscopicoEndoscopia intraoperatoriaGlicerolo (per ponfi sottomucosi)
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